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Genetically engineered mice - メーカー・企業と製品の一覧

Genetically engineered miceの製品一覧

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Transgenic Group Comprehensive Catalog Digest Edition

Transgenic Group Comprehensive Catalog Digest Edition

We offer a wide range of products and services related to mice and genetic analysis!

This catalog is a comprehensive guide from a company that engages in the production of gene knockout mice, provides genetic information to research institutions such as universities and pharmaceutical companies, sells reagents, and conducts non-clinical and clinical trial outsourcing, as well as pathology diagnostics. It includes various products and services related to the production of genetically modified mice, such as "Conditional Knockout Mouse Production," and gene analysis-related services like "GeneChip Transcriptome Array (Human, Mouse, Rat) 2.0 Analysis" and "GANP(R) Monoclonal Antibody Production." [Overview of Contents] ■ Mice ■ Gene Analysis Related ■ Proteins ■ CRO ■ Pathology Research Outsourcing, etc. *This catalog is a digest version. Please contact us if you need the full version. *For more details, please refer to the catalog or feel free to contact us.

  • Cell-related contract

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Contract for the production of genetically modified mice: Creation of transgenic mice.

Contract for the production of genetically modified mice: Creation of transgenic mice.

Tissue samples are taken from the obtained offspring! They are produced by microinjection into fertilized eggs.

Our company is engaged in the production of "transgenic mice." Transgenic mice are created by purifying DNA fragments of the expression unit that includes a promoter, the gene to be expressed, and a polyA sequence from plasmid DNA, and then microinjecting them into fertilized eggs. From the resulting offspring, tissue samples are collected, and genotyping PCR is performed to investigate the insertion of the injected gene into the genome, thereby identifying the founder mouse (FO). [Features] - Production by injecting the gene expression unit into fertilized eggs of the C57BL/6 strain - Forced expression of the gene in mouse individuals - Specific expression can be achieved by selecting the promoter - Strong expression throughout the body is also possible by using the CAG promoter *For more details, please refer to the PDF materials or feel free to contact us.

  • Animal cells

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Genetically modified mouse: "Knock-in mouse production"

Genetically modified mouse: "Knock-in mouse production"

Production of KI mice, it is possible to create KI mice at specific genetic loci!

We would like to introduce the "Knock-in Mouse Production" offered by Unitec Co., Ltd. It is possible to create disease model mice by introducing disease-causing SNPs into mice. We can produce mice for in vivo localization and dynamics visualization of target proteins, as well as mice that express human target proteins within their bodies. As additional options, we offer increased targeting vector supply and the production of linked embryos (200 units). We also accept requests for the production of transgenic mice. 【KI Mouse Production Process (Excerpt)】 ■ Design and construction of targeting vectors ■ Establishment of homologous recombination ES cells (derived from C57BL/6J) ■ Production of chimeric mice ■ Production of F1 heterozygous mice ■ Production of Neo sequence removal mice *For more details, please refer to the PDF document or feel free to contact us.

  • Other contract manufacturing

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